This article showcases our top picks for the best Biotechnology companies based in Spain. These startups and companies are taking a variety of approaches to innovating the Biotechnology industry, but are all exceptional companies well worth a follow.
We meticulously selected companies ranging from cutting-edge startups to established brands based on their outstanding performance in the following categories:
- Innovation: Innovative ideas, innovative route to market, innovative product
- Growth: Exceptional growth, exceptional growth strategy
- Management, diversity and/or societal impact
Top Spanish Biotechnology Startups
Data sourced from Crunchbase and SemRush.
Neuroelectrics: This enterprise specializes in the intersection of digital technology and neuroscience, focusing on the diagnosis and therapeutic intervention of neurological disorders. It employs non-invasive brain stimulation and monitoring techniques to promote brain health and treat various conditions.
Quibim: Hailing from Valencia, this leader in medical imaging analysis provides comprehensive solutions for the analysis of radiological scans and biomarkers. Their technology is designed to extract quantitative data, offering objective insights into patient health.
Oryzon Genomics: As a clinical-stage biopharmaceutical entity, it is at the forefront of epigenetic drug development. The company’s pipeline includes innovative therapies targeting a variety of diseases, with a particular focus on oncology and neurodegenerative disorders.
INBRAIN Neuroelectronics: Innovating in the field of bioelectronics, this company leverages the unique properties of graphene to develop neural interfaces. Their technology promises to be minimally invasive while offering high-resolution brain monitoring and stimulation capabilities.
SANIFIT: This biotech venture is focused on advancing treatments for calcification disorders, conditions where calcium builds up in body tissues causing damage and complications. Their research addresses a significant unmet medical need by targeting the calcification process at the molecular level.
Medlumics: Operating at the nexus of biotechnology and photonics, Medlumics is developing cutting-edge optical systems for medical applications. Their innovations include minimally invasive devices designed to improve diagnostic accuracy and therapeutic outcomes.
VIVEbiotech: As a CDMO, this firm is deeply embedded in the gene therapy space, specializing in the production of Lentiviral vectors. Their expertise encompasses both development and manufacturing, ensuring the delivery of high-quality vectors for clinical and commercial use.
Cubiq Foods: Positioned in the alternative food industry, this company focuses on developing healthier fat alternatives through cell-based technologies. They offer solutions that have the potential to revolutionize the food industry with products that are both healthy and environmentally friendly.
Minoryx Therapeutics: Dedicated to addressing the challenge of genetic diseases, this company develops small-molecule drugs known as pharmacological chaperones. These drugs are designed to stabilize and restore the function of defective proteins, offering a potential treatment for a variety of genetic disorders.
Telomere Therapeutics: Originating from the University of Barcelona, this spinoff is pioneering the use of telomerase gene therapy for the treatment of pulmonary fibrosis. By targeting the telomeres at the ends of chromosomes, they hope to develop novel therapies that can reverse or halt the progression of age-related diseases.
Bioo: This innovative company is pioneering the generation of electricity from the biological activity of soil. Their technology capitalizes on the natural processes of plants and microorganisms to create sustainable energy sources. The applications of Bioo’s technology range from small-scale installations to larger green energy projects.
Universal Diagnostics: With a focus on early cancer detection, this diagnostics company is developing blood-based tests that are minimally invasive. Their platform is geared towards identifying cancer at its earliest stages when treatment is most effective. Utilizing advanced biomarker technology.
Alga Energy: Engaged in the cultivation of microalgae, Alga Energy is spearheading efforts to produce clean energy and high-value compounds such as omega-3 oils. Their proprietary photobioreactor technology optimizes the growth of algae, enabling the production of biofuels and other products in an environmentally friendly manner.
Veritas Intercontinental: This genetics company is driven by the mission to unlock the potential of the human genome to enhance the length and quality of life. Through genetic testing and personalized analysis, they empower individuals with knowledge about their health predispositions and potential.
Capital Cell: As Europe’s first equity crowdfunding platform dedicated to the biotech and healthcare sectors, Capital Cell facilitates investment in cutting-edge medical and health-related startups. Their platform connects innovative companies with a community of investors eager to support advancements in life sciences.
Highlight Therapeutics: A clinical-stage biopharmaceutical company engaged in the development of drugs aimed at different types of cancer. Highlight Therapeutics is pioneering new approaches to immunotherapy, seeking to improve outcomes for patients with unmet medical needs in oncology.
Devicare: Specializes in the design of medical devices for point-of-care diagnostic and management of chronic diseases. Devicare’s solutions empower patients to monitor and manage their health conditions from the comfort of their homes, improving their quality of life and enabling better chronic disease outcomes.
Ona Therapeutics: Focuses on the research and development of biologic treatments targeting metastatic cancer. The company’s innovative approach aims to disrupt the mechanisms of cancer spread, with the ultimate goal of delivering new therapeutic options for patients battling with advanced stages of the disease.
STAT-Dx: Develop diagnostic products that enable near-patient testing for healthcare professionals. STAT-Dx’s technology strives to simplify and expedite the diagnostic process, facilitating timely and accurate medical decisions directly at the point of care.
Graphenea: A leading company in the field of graphene production, specializing in high-quality CVD graphene wafers and Graphene Oxide materials. Graphene a’s products serve as a foundation for developing advanced materials across various industries, including electronics, energy, and biotechnology.
Accure Therapeutics: A clinical-stage pharmaceutical company with a dedicated research and development engine in the central nervous system (CNS) therapeutic area. Accure Therapeutics focuses on addressing neurological and psychiatric disorders through innovative CNS pharmacological treatments.
Ability Pharmaceuticals: A drug discovery and development firm that works on identifying novel pharmaceutical compounds. The company’s expertise lies in progressing these compounds from the concept stage through to clinical trials, to treat various diseases.
SOM Biotech: Operates as a drug innovation company with a unique AI-based drug discovery platform. It boasts a strong pipeline of potential treatments for orphan central nervous system (CNS) diseases, showcasing its commitment to tackling rare medical conditions.
Algenex: A biotech company developing vector-based technologies to enable the efficient manufacture of recombinant proteins. Algenex’s approach has the potential to revolutionize the production of biological agents for various applications in the life sciences sector.
Atrys Health: A biomedical firm providing advanced diagnostic services and excellent medical treatments. Atrys Health integrates multiple medical specialties to offer comprehensive patient care and innovative healthcare solutions.
Aelix Therapeutics: Engages in the development of therapeutic vaccines and immunotherapies for HIV infection. The company aims to create treatments that could change the management of HIV, focusing on improving the quality of life for those living with the virus.
ARTHEx Biotech: Specializes in the development of AntagomiR oligonucleotides as a novel therapeutic approach to treat patients with Myotonic Dystrophy, aiming to address the genetic causes of this debilitating disease.
AptaTargets: A biopharmaceutical company dedicated to developing innovative therapeutics. The company’s work is centered on discovering and progressing drug candidates with the potential to become transformative treatments for various diseases.
Aortyx: Committed to providing cutting-edge solutions for aortic diseases. Aortyx is focused on developing endovascular treatments that are less invasive and more effective than traditional surgical approaches, aiming to improve patient outcomes in vascular health.
Peptomyc: Concentrates on the development of novel cell-penetrating peptides that target the Myconcoprotein, offering a new generation of cancer treatments. Their research is dedicated to disrupting cancer cell proliferation and survival by interfering with critical cellular pathways.
Cebiotex: Offers state-of-the-art nanofiber technology for drug delivery applications. Their electrospun nanofiber technology is utilized for innovative drug release systems, enhancing the therapeutic efficacy and safety profiles of various drugs.
Pharmacelera: Uses quantum mechanics (QM) and Machine Learning (ML) to accelerate drug discovery processes. Their computational platform aims to identify and optimize promising drug candidates with higher precision and speed than traditional methods.
Splice Bio: A biotech entity based on pioneering intein technologies from the Muir Lab at Princeton University. The company leverages these technologies to develop novel gene therapy solutions, with a focus on addressing genetic diseases.
Bitbrain: Merges neuroscience with engineering to create advanced neurotechnology for a range of applications, including research, health, and marketing. Bitbrain’s solutions are at the forefront of understanding and utilizing brain activity for various innovative applications.
BioFlyTech: A Technology-Based Company specializing in the artificial breeding and intensive production of insect biomass. BioFlyTech focuses on sustainable solutions for the agriculture and food industries, harnessing the potential of insects as a resource-efficient alternative.
Made of Genes (Genomcore): Positioned as a personal genomics entity, MOG is at the forefront of unlocking the potential of individualized genetic information. The company endeavors to provide insights and solutions tailored to each individual’s unique genetic blueprint, ushering in a new era of personalized healthcare and wellness.
Roka Furadada: This innovative company is dedicated to combating skin cancer by conducting research, development, and production of active ingredients. Roka Furadada is on a mission to mitigate the incidence of skin cancer by creating groundbreaking solutions and promoting proactive skin health.
Mimetis Biomaterials: A pioneering company in the realm of biomimetics, Mimetis Biomaterials specializes in designing, manufacturing, and marketing regenerative bone solutions. With applications in both the dental and orthopedic sectors, the company aims to emulate the natural structure and function of bone to foster effective regeneration.
RawData: A B2B Software-as-a-Service entity powered by AI, RawData delivers actionable insights in the agricultural sector. Without relying on IoT, the company provides precise crop predictions including optimal harvest times and potential plant diseases, empowering businesses to make data-driven decisions.
ZeClinics: As a Startup Contract Research Organization (CRO), ZeClinics provides an innovative outsourcing solution for the safety and efficacy screening of chemical compounds. Utilizing zebrafish as a model organism, the company offers rapid and efficient assessments, streamlining the drug development process.
Natac: Operating at the nexus of nature and science, Natac is committed to researching, developing, and sustainably producing ingredients derived from natural sources. Through its initiatives, the company seeks to harness the therapeutic and nutritional potential of nature, providing holistic solutions for health and well-being.
Lipopharma: An avant-garde company that zeroes in on the design and development of synthetic bio-active lipids. These novel compounds interact with proteins implicated in a plethora of serious diseases, representing a promising therapeutic approach.
Senolytic Therapeutics: Operating under the moniker STX, this pharmaceutical firm is breaking new ground by developing a novel class of medicines. By specifically targeting damaged cells, Senolytic Therapeutics aims to revolutionize treatment paradigms and improve patient outcomes.
Aglaris Ltd: Pushing the boundaries of stem cell research, Aglaris is in the process of developing an automated cell culture bioreactor. This cutting-edge technology is poised to revolutionize the mass production of human stem cells, meeting the ever-growing demand in regenerative medicine.
nLife Therapeutics: A trailblazing biopharmaceutical development entity, nLife Therapeutics is devoted to the creation of novel treatments for Central Nervous System (CNS) diseases. Through its innovative approaches, the company seeks to address some of the most pressing challenges in neurology.
Pulmobiotics: A dynamic life sciences company that is currently in the pre-clinical development phase. Pulmobiotics is engaged in cutting-edge research, striving to bring forth groundbreaking solutions in the field of pulmonary health.
GlyCardial Diagnostics: A spin-off entity originating from the IR-Hospital de la Santa Creu i Sant Pau and the Spanish National Research Council. The company’s focus remains on diagnostic solutions, harnessing advanced research to address healthcare challenges.
Regemat 3D: REGEMAT3D stands as a pioneer in the realm of 3D printing for regenerative therapies. By harnessing the potential of 3D bioprinting, the company aims to transform the landscape of regenerative medicine, providing bespoke solutions for tissue and organ repair.
Origo Biopharma: A cutting-edge biotech company engaged in pioneering research and development. With a strong foundation in biotechnology, Origo Biopharma is on a mission to bring forth innovative solutions to address unmet medical needs.
Laminar Pharma: This biopharmaceutical firm specializes in the discovery, rational design, and early clinical development of new drugs based on Membrane Lipid Therapy (MLT). Through its unique approach, Laminar Pharma aims to address various health challenges with precision.
VEnvirotech Biotechnology: With a commitment to sustainability, this company transforms organic waste into bioplastics. Adopting a circular approach, Envirotech Biotechnology transforms waste into value, offering environmentally friendly alternatives to conventional plastics.
Vytrus Biotech: Originating as a spin-off from the Faculty of Pharmacy at the University of Barcelona, Vytrus Biotech is deeply rooted in academic research. The company is at the forefront of innovative biotechnological solutions, leveraging its expertise to address challenges in healthcare and beyond.
Amadix: This biotech company is dedicated to crafting diagnostic tools for personalized cancer care. It is focused on innovations that could help personalize treatment strategies. Their approach may significantly enhance the effectiveness of oncology therapies. Amadix’s work has the potential to transform patient outcomes in cancer care.
Zymvol Biomodeling: Zymvol specializes in using computer simulations to accelerate enzyme discovery and development. Its technology aims to streamline the enzyme engineering process. By predicting enzyme behavior, they reduce research time and costs. Zymvol stands at the intersection of biology and computational science.
Genmedica Therapeutics: Genmedica is a biotech entity targeting the treatment of type 2 diabetes. The company is in the development stage, working on innovative therapeutic solutions. Its focus is on creating drugs that could potentially revolutionize diabetes care. They aim to impact a condition that affects millions worldwide.
DeepUll: DeepUll is pioneering in biotech with a focus on early-stage sepsis diagnosis. Their new diagnostic system aims to be groundbreaking in medical technology. This could lead to a significant reduction in sepsis-related morbidity. DeepUll’s initiative represents a critical advancement in emergency medicine.
Connecta Therapeutics: Connecta is working on novel CNS treatments, tackling diseases with unmet medical needs. Their research could lead to breakthrough therapies for neurological conditions. The focus is on innovation in central nervous system care. Connecta’s work promises to open new possibilities for patient treatment.
InnoUp Farma: InnoUp Farma is a nanomedicine company pioneering nano-scale pharmaceuticals. Their focus on highly targeted therapies could redefine treatment modalities. They are exploring the potential of nanotechnology to minimize side effects. InnoUp is at the cutting edge of precision medicine.
BDi Biotechnology Group: BDi Biotech specializes in managing research and turning discoveries into products. Their expertise spans contract research and project management. BDi supports companies across various stages of product development. Their work facilitates the transition from lab research to market-ready solutions.
Doitplenoptic: Doitplenoptic is developing new plenoptic technology for smarter product development. They aim to revolutionize imaging in clinical and industrial applications. Their technology promises to enhance diagnostic capabilities. Doitplenoptic merges optics and informatics for advanced imaging solutions.
NIMGenetics: NIMGenetics is a Spanish biomedicine company that emphasizes genetic diagnostics. They decipher complex DNA information for better health outcomes. Their work aids in understanding genetic predispositions to diseases. NIMGenetics is pioneering personalized healthcare through genetics.
Inbiomotion: Inbiomotion focuses on creating biomarkers to predict bone metastasis in cancer. Their research could change the prognosis and treatment of cancer. They aim to personalize cancer care by understanding metastatic patterns. Inbiomotion’s work is pivotal in the field of oncology.
HEALTH IN CODE: HEALTH IN CODE leads in diagnosing genetic cardiac conditions in Europe. From diagnosis to prognosis, they cover a broad spectrum of cardiac care. Their work enables personalized treatment plans for inherited heart diseases. HIC is an innovator in cardiological genetic research.
ABAC Therapeutics: ABAC Therapeutics develops new, targeted antibiotics for severe infections. They are at the forefront of addressing antibiotic resistance. ABAC is creating treatments specific to patients’ needs. Their antibiotics represent a new hope against resistant bacterial strains.
AB-BIOTICS: AB-BIOTICS is engaged in biotechnological research and solution distribution. They protect and distribute proprietary biotechnological advancements. The company is a key player in healthcare and biomedicine innovation. AB-BIOTICS’ solutions have wide-ranging implications for patient care.
DAN*NA: DANNA is shaping the future of sustainable materials through bioplastics. They focus on creating value from organic waste. Their approach to bioplastics could drastically reduce environmental impact. DANNA’s technology represents a leap forward in eco-friendly materials.
IDP Pharma: IDP Pharma has developed a novel drug for multiple myeloma. They are also pioneering discovery programs for cancer treatment. Their first-in-class drug represents a significant therapeutic advance. IDP Pharma’s work is critical for patients with this plasma cell cancer.
TellmeGen: TellmeGen provides insights into genetic health risks and sensitivities. Their services allow for proactive health and wellness planning. They leverage genetic data to inform on potential future illnesses. TellmeGen is transforming personal healthcare management through genomics.
Oncomatryx: Oncomatryx focuses on the tumor microenvironment to develop cancer therapies. Their work is crucial in understanding cancer progression and spread. By targeting the microenvironment, they aim for more effective treatments. Oncomatryx is a key player in advancing oncological therapeutics.
Histocell SL: Histocell SL is innovating in regenerative medicine with cell therapy products. They also develop novel medical devices for tissue repair. They aim to heal and replace damaged tissues and organs. Histocell SL is at the forefront of regenerative healthcare solutions.
NANOGAP: NANOGAP commercializes advanced nanomaterials for various industries. Their proprietary nanoparticle technology has wide applications. They focus on innovation in electronics, medicine, and energy. NANOGAP is pushing the boundaries of materials science for future technologies.
Fastbase Solutions: Fastbase Solutions harnesses a cancer diagnostics platform designed to improve detection and treatment. It provides clinicians with precise diagnostic tools. Fastbase is enhancing the path to personalized cancer therapy. Their platform could be transformative in oncology diagnostics.
Gyala Therapeutics: Gyala is at the forefront of developing CAR-T therapies for blood cancers. Their research could bring new hope to patients with hematological malignancies. They’re innovating in the field of immunotherapy. Gyala’s work is pivotal in advancing cancer treatment.
PaloBiofarma: PaloBiofarma is engaged in drug discovery through medicinal chemistry. Their innovative approach aims to uncover new therapeutic compounds. Their research has the potential to lead to breakthrough medications. PaloBiofarma’s work merges chemistry and biology for health solutions.
Symborg: Symborg develops bio-fertilizers, revolutionizing agriculture with sustainable solutions. Their products aim to increase crop yield and health. They focus on innovative, environmentally friendly agricultural practices. Symborg’s R&D is crucial for advanced and sustainable farming.
Aptadel Therapeutics: Aptadel Therapeutics is a pre-clinical company exploring novel biomedical solutions. Their research phase is critical for future clinical applications. Citadel is committed to advancing medical science. Their therapeutic innovations hold promise for future healthcare treatments.
AVX Pharma: AVX Pharma is developing innovative drugs for significant ophthalmic conditions. Their focus on unmet medical needs in eye care is critical. They’re dedicated to enhancing vision health and quality of life. AVX Pharma’s work could lead to pivotal ophthalmological advancements.
Genbioma: Genbioma is pioneering health solutions targeting the human microbiome. Their goal is to promote well-being through microbial balance. They’re at the intersection of health and biotechnology. Genbioma’s approach could redefine preventive and therapeutic health strategies.
Agrasys: Agrasys is an agri-food company rooted in technological innovation. They aim to improve food production and quality. Their work bridges agriculture and scientific research. Agrasys is committed to food innovation and sustainable practices.
ADmit Therapeutics: ADmit Therapeutics is developing an early diagnostic test for Alzheimer’s disease. Their biotechnology could be key in combating this neurodegenerative condition. Early detection is vital for treatment efficacy. ADmit’s research is a beacon of hope for Alzheimer’s patients.
Laboratorios Larrasa: As Extremadura’s first biotech ‘spin-off’, Laboratorios Larrasa is leading regional biotechnological innovation. Their research contributes significantly to the field. They’re recognized for scientific advancement and regional development. Their presence underscores the university’s commitment to knowledge of industry.
Mecwins: Mecwins enhance disease detection with ultra-sensitive immunoassays for critical illnesses. Their oncology, cardiovascular, and infectious disease focus is groundbreaking. Mecwins’ technology is key in early and accurate disease diagnosis. They are transforming the landscape of medical diagnostics.
Iproteos: Iproteos emerged from a technology transfer initiative from IRB Barcelona and the University of Barcelona. Their focus is on bringing academic discoveries to market. They work at the crossroads of research and commercialization. Iproteos stands out for bridging the gap between science and therapy.
Leukos Biotech: A biopharmaceutical company, Leukos Biotech is engaged in the discovery and development of new cancer treatments. Their focus on advancing oncology therapeutics is crucial. Leukos is committed to finding solutions for complex medical challenges. They strive to improve outcomes for cancer patients.
OneChain Immunotherapeutics: OneChain Immunotherapeutics (OCI) crafts CAR-T cell therapies for leukemia. They are a leader in advancing cellular immunotherapy. OCI’s work is instrumental in developing personalized cancer treatments. Their therapeutic strategies are groundbreaking in hematologic oncology.
Telum Therapeutics: Telum Therapeutics is a biotech enterprise working on novel drug developments. They’re in the stages of research where breakthroughs can emerge. Tulum is poised to contribute substantially to the medical field. Their work could bring new treatment options to patients.
Vivia Biotech: Vivia Biotech excels in precision medicine, offering tailored solutions for clinicians and patients. Their work is pivotal in personalized healthcare. Vivia is at the forefront of individualized treatment, aiding in optimal therapeutic strategies. They help personalize the fight against diseases.
Gate2Brain: Gate2Brain utilizes patented peptide technology to enhance drug delivery. Their innovative approach aims to surpass the blood-brain barrier. Gate2Brain’s work could revolutionize treatment for neurological disorders. They’re pioneering new frontiers in biopharmaceutical development.
Ikan Biotech: Ikan Biotech is a CRO specializing in zebrafish-based preclinical services and antibiotics development. Their work bridges drug discovery and model organism research. Ikan is known for accelerating preclinical testing with innovative methodologies. They play a key role in therapeutic development.
Biohope: Biohope is committed to improving organ transplantation outcomes through diagnostic and therapeutic solutions. Their innovations could enhance transplant success rates. Biohope’s work is vital for patient care in transplant medicine. They’re improving the lives of those needing organ transplants.
Bicosome: Bicosome delivers cutting-edge cosmetic and dermo-pharmaceutical ingredients. Their patented platform is a game-changer in skin care. Bicosome’s biocompatible systems enhance product efficacy. They’re leading the way in advanced skin health solutions.
RheoDx: RheoDx’s portable device offers precise diagnostics for hematological diseases from a single blood drop. Their technology brings efficiency to blood disorder testing. RheoDx is innovating in the field of in-vitro diagnostics. Their advancements could transform hematological disease management.
AROMICS: is dedicated to discovering and developing new drugs and diagnostic methods. Their focus is on tackling significant human health diseases. AROMICS’ work in drug development is essential for advancing treatment options. They’re a key player in biotechnological innovation.
Ahead Therapeutics: Ahead Therapeutics uses proprietary technology to develop auto-immune disorder treatments. Their work could change the landscape of autoimmune therapies. Ahead Therapeutics is at the vanguard of curative interventions. They’re forging paths towards alleviating auto-immune challenges.
RUTI Immune: RUTI Immune is in the process of developing a vaccine against Covid-19 and other pathogens. Their work is vital in the global fight against pandemics. RUTI’s vaccine research could be transformative for public health. They’re playing a crucial role in pandemic preparedness and response.
Arkyne Technologies: Arkyne Technologies specializes in renewable energy innovations. Their focus on sustainable power sources is key to a greener future. Arkyne is pioneering energy solutions to combat climate change. Their technologies are leading a shift towards renewable energy reliance.
AWSensors: AWSensors designs and commercializes high-precision tools for characterizing acoustic resonators. Their technology is central to material analysis. AWS sensors’ instruments are essential for research and development in various industries. They’re redefining precision in material science.
Onalabs Healthcare: Onalabs is revolutionizing non-invasive health monitoring with sweat-based biosensors. Their wearable technology is a breakthrough in patient care. Onalabs is leading the charge in innovative health-tracking solutions. Their biosensors could greatly improve personal health management.
TBIOM: TBIOM is a biotech startup aimed at developing sustainable medical products. They focus on creating solutions for broad health challenges. TBIOM is contributing to a sustainable and healthier future. Their efforts are crucial for improving global health conditions.
NBD | Nostrum Biodiscovery: Nostrum Biodiscovery is forging new drugs with the aid of AI and supercomputing. Their cutting-edge approach expedites drug discovery. NBD’s integration of technology and biology is innovative. They’re pivotal in creating the next generation of pharmaceuticals.
OXOlife: Oxolife is a clinical-phase biotech company focusing on fertility enhancement. They’re pioneering treatments to assist reproduction. OXOlife’s work is crucial for many seeking help with conception. Their research holds promise for reproductive health advancements.
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